100% Apio juice - Apio Flow 500ml

Potential Health Benefits

1. A natural profile of plant antioxidants

Celery contains a range of phenolic compounds, including caffeic acid, p-coumaric acid and ferulic acid, as well as flavonoids such as apigenin, luteolin and kaempferol. In scientific reviews, these compounds have been linked to celery’s antioxidant activity and to mechanisms involved in the body’s response to oxidative stress. [1,2]

This does not mean that celery juice itself treats conditions related to oxidative stress. Rather, celery is an interesting dietary source of naturally occurring phytochemicals.

2. Apigenin and luteolin — two particularly interesting celery flavonoids

Apigenin has been identified in celery stalks, while luteolin is also present in different parts of the celery plant. Both belong to the flavone family and have been widely studied in relation to oxidative balance, inflammatory signalling pathways and vascular physiology. [2–4]

An important detail is that apigenin concentrations can vary considerably between celery varieties and plant parts, and celery leaves generally contain higher concentrations than the stalks. [3]

3. Scientific interest in blood-pressure balance

Celery has attracted particular research interest in the context of blood-pressure regulation. A 2025 systematic review and meta-analysis included 10 randomised controlled trials involving 511 adults and found an overall reduction in blood-pressure measurements following the use of different celery preparations. [5]

Potential mechanisms discussed in the literature include celery compounds such as 3-n-butylphthalide, apigenin and other bioactive substances, which have been associated with vascular-tone regulation in experimental models. [6]

However, there is an important limitation: much of the better-quality human research has investigated celery seed extracts or other concentrated preparations, rather than ordinary celery stalk juice. Apio Flow should therefore not be positioned as a product that lowers blood pressure.

4. Scientific interest in glucose and lipid metabolism

The same 2025 meta-analysis also reported associations between celery preparations and changes in fasting blood glucose and triglyceride levels, while findings for total cholesterol, LDL and HDL were less consistent. [5]

This makes celery scientifically interesting in the context of metabolic balance, but once again, results from concentrated extracts and seed preparations should not be directly transferred to Apio Flow celery stalk juice.

5. Celery stalks contain more than just water

Studies comparing different parts of the celery plant have identified minerals and plant antioxidants in the stalks, while phytochemical research has also confirmed the presence of phenolic compounds in celery stalk tissue. [4,7]

For this reason, Apio Flow does not need to be presented as a “detox miracle drink.” A more scientifically accurate and credible story is that of a green vegetable with a naturally diverse phytochemical profile.

6. What do we know specifically about celery stalk juice?

Clinical research specifically on celery juice in humans remains very limited. One published case report described an individual with hypertension whose blood pressure decreased over six months while consuming celery juice daily. However, the author explicitly noted that a single case cannot establish a cause-and-effect relationship. [8]

This is important for the way we communicate Apio Flow: the strongest scientific foundation comes from the phytochemical composition of celery and the broader body of research on Apium graveolens, rather than from clinically proven therapeutic effects of celery stalk juice itself.

Important note on the scientific evidence

A significant proportion of the clinical research on celery’s potential effects on blood pressure and metabolic markers has been conducted using celery seeds, extracts or concentrated preparations, rather than celery stalk juice.

In addition, the authors of the 2025 meta-analysis noted substantial heterogeneity between studies and relatively small participant numbers. [5]

Therefore, the research discussed on this page should be understood as evidence relating to celery and its bioactive compounds, not as proof that Apio Flow can treat, prevent or cure any disease.

References

[1] Kooti W., Daraei N. A Review of the Antioxidant Activity of Celery (Apium graveolens L). Journal of Evidence-Based Complementary & Alternative Medicine. 2017.

[2] Sowbhagya H.B. Chemistry, technology, and nutraceutical functions of celery (Apium graveolens L.): an overview. Critical Reviews in Food Science and Nutrition. 2014;54(3):389–398.

[3] Hostetler G.L. et al. Flavones: Food Sources, Bioavailability, Metabolism, and Bioactivity. Advances in Nutrition.2017.

[4] Golubkina N. et al. Yield, Growth, Quality, Biochemical Characteristics and Elemental Composition of Plant Parts of Celery Leafy, Stalk and Root Types Grown in the Northern Hemisphere. Plants. 2020.

[5] Liu D., Zhao H., Xu H., Hu J. Effects of celery (Apium graveolens) on blood pressure, glycemic and lipid profile in adults: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Nutrition.2025;12:1597680.

[6] Alobaidi S., Saleh E. Antihypertensive Property of Celery: A Narrative Review on Current Knowledge. 2024.

[7] Nair V. et al. Mineral Content Variation in Leaves, Stalks, and Seeds of Celery (Apium graveolens L.) Genotypes.2022.

[8] Illes J.D. Blood Pressure Change After Celery Juice Ingestion in a Hypertensive Elderly Male. Journal of Chiropractic Medicine. 2021;20(2):90–94.